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目的:探讨慢性心力衰竭(CHF)患者心率减速力(DC)与室性心律失常(VA)的相关性。方法:选择146例CHF患者为研究对象,同期选择108例体检健康人群为对照组。所有入选者均行24 h动态心电图和超声心动图检查,离线计算DC值、心率变异性(HRV)时域指标,比较两组数据,分析CHF患者的DC值、HRV时域值与VA之间的关系。结果:CHF组DC值和HRV时域值均比对照组显著降低(P<0.01);CHF组的DC值、正常R-R间期标准差(SDNN)、每5 min R-R间期平均值标准差(SDANN)及相邻R-R间期差值大于50 ms的百分数(p NN50)均与VA程度呈负相关(P<0.05)。结论:CHF患者DC值和HRV时域指标越低,越易发生恶性VA。早期对CHF患者进行干预性治疗有利于降低恶性VA发生率及患者死亡率。
Objective: To investigate the relationship between heart rate deceleration (DC) and ventricular arrhythmia (VA) in patients with chronic heart failure (CHF). Methods: A total of 146 patients with CHF were selected as study subjects, and 108 healthy subjects were selected as the control group in the same period. All participants underwent 24 h ambulatory electrocardiogram and echocardiography, offline calculation of DC value and heart rate variability (HRV) time domain indicators, compared two groups of data, analysis of DC patients with CHF, HRV between the time domain values and VA Relationship. Results: The values of DC and HRV in CHF group were significantly lower than those in control group (P <0.01). The DC value in CHF group, SDNN in normal group, and standard deviation in RR interval in every 5 min SDANN) and the percentage of inter-RR interval greater than 50 ms (p NN50) were negatively correlated with VA (P <0.05). Conclusion: The lower the DC value and the HRV time domain index in patients with CHF, the more prone to malignant VA. Early intervention in patients with CHF is conducive to reduce the incidence of malignant VA and patient mortality.