轻度高血压病患者血管及心脏重构的研究

• 作 者: 陈碧莲 张波
• 机 构: 中南大学湘雅医院老干科,中南大学湘雅医院老干科,中南大学湘雅医院老干科,中南大学湘雅医院老干科,中南大学湘雅医院超声科,中南大学湘雅医院超声科 长沙410078,长沙410078,长沙410078,长
• 出 处: 中国现代医学杂志
• 发表日期: 2003年02期
• 关键词: 轻度高血压 心脏重构 动脉重构 左室重量指数 射血分数 颈动脉壁 中膜厚度 舒张功能减退 超声心动图检测 僵硬度

目的 :探讨轻度高血压病患者血管及心脏重构。方法 :应用超声技术检测轻度高血压病患者颈动脉内膜-中膜厚度 (IMT)、横断面顺应性 (CSC)和容积扩张性 (VD)及心脏左室重量指数 (LVMI)、射血分数 (EF)、舒张早期与晚期二尖瓣峰值速度比值 (E/A)。分析IMT、CSC、VD与E/A、LVMI的相关性。结果 :轻度高血压病组颈动脉IMT增厚 ,CSC和VD降低 ,LVMI增高 ,E/A降低 (P <0 .0 5 )。E/A与IMT呈负相关 ,与CSC呈正相关 ,LVMI与IMT呈正相关 ,与CSC呈负相关 (P <0 .0 1)。结论 :轻度高血压病患者发生了血管及心脏重构。

Objective: To investigate the vascular and cardiac remodeling in patients with mild hypertension. Methods: The carotid arterial intima - media thickness (IMT), cross - sectional compliance (CSC), volume expansion (VD) and left ventricular mass index (LVMI) Score (EF), early and late diastolic mitral peak velocity ratio (E / A). Analysis of IMT, CSC, VD and E / A, LVMI correlation. Results: The carotid IMT was thickened, the CSC and VD were decreased, the LVMI was increased and the E / A was decreased in mild Hypertension group (P <0.05). E / A was negatively correlated with IMT and positively correlated with CSC. LVMI was positively correlated with IMT and negatively correlated with CSC (P <0.01). Conclusion: Vascular and cardiac remodeling occurred in patients with mild hypertension.