论文部分内容阅读
为研究用肉毒杆菌毒素A(BotulinumtoxinA简称BTXA)治疗先天性眼球震颤的疗效,并进一步探讨其与手术等其他方法治疗该病的优缺点。采用兰州生物制品所生产的BTXA一定剂量注射入相应的眼外肌,比较注射前与注射后一周和一月的视功能、眼震和三级视功能,用统计学方法处理,确认该治疗是否有效。结果:注药后一月的近视力比注药前提高,有明显统计学差异。远视力的变化无明显统计学差异。注药后一月与注药前相比,3m及33cm原眼位的眼震振幅或震频降低有明显统计学差异。三级视功能在注药前后无明显统计学差异。最小震强出现的位置虽在注药前后无显著差异,但该处眼震振幅降低有显著差异。代偿头位的矫正率在注药后一月为80%。结论:该方法治疗先天性眼球震颤有效。
To investigate the efficacy of Botulinum toxin A (BTXA) in the treatment of congenital nystagmus and to further explore the advantages and disadvantages of other methods such as surgery and surgery for the treatment of this disease. A dose of BTXA produced by Lanzhou Biological Products was injected into the corresponding extraocular muscles to compare the visual function, nystagmus and tertiary visual function before injection and one week and one month after injection, and to determine whether the treatment is statistically effective. Results: One month after injection, the near visual acuity was higher than that before injection, with significant statistical difference. No significant difference was observed in the changes of far vision. Compared with before injection, the nystagmus amplitude or shock frequency of 3m and 33cm original oculomotion decreased obviously in January after injection. Three-level visual function in the injection before and after no significant difference. Although there was no significant difference in the location of minimum shock before and after injection, there was a significant difference in the reduction of nystagmus amplitude. The rate of head-to-head correction was 80% in January after injection. Conclusion: This method is effective in treating nystagmus.