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为了解不同疗法治疗鼻咽癌的效果 ,将 16 3例鼻咽癌病人随机分为 3组 :外照射 +中药 +腔内后装组(EIAIRC) ;外照射 +中药组 (EIC)和单纯外照射组 (SRT)。全部病人行常规放疗。EIAIRC组鼻咽外照射剂量为 5 6～ 6 0Gy,腔内放疗每次 8Gy ,共 2次 ;EIC及SRT组外照射剂量 6 8～72Gy。三组中有颅底骨破坏者小野补量 10Gy。EIAIRC和EIC组于放疗期间配合中药治疗。结果显示 3组病人的 3,5年生存率以及局部复发、远处转移各组间均无统计学差异 ;但放疗伍用中药可减轻鼻咽癌放疗的急性反应。提示早期鼻咽癌外照射配合腔内治疗 ,可减少外照射剂量 (减轻放射损伤 ) ;中药不增加远处转移 ,但可缓和不良反应
To understand the effect of different therapies on nasopharyngeal carcinoma, 163 patients with nasopharyngeal carcinoma were randomly divided into 3 groups: external beam + Chinese medicine + intracavitary after-loading group (EIAIRC); external beam + Chinese herb group (EIC) Irradiation group (SRT). All patients underwent routine radiotherapy. EIAIRC group, the dose of nasopharyngeal radiation was 56 ~ 60Gy, intraluminal radiotherapy 8Gy each time, a total of 2 times; EIC and SRT group dose of 68 ~ 72Gy. Three groups in the skull base damage Xiaogan volume 10Gy. EIAIRC and EIC group with Chinese medicine treatment during radiotherapy. The results showed that the 3 and 5-year survival rates, as well as local recurrence and distant metastasis of the three groups of patients were not statistically different; however, radiotherapy combined with traditional Chinese medicine can reduce the acute response to radiotherapy of nasopharyngeal carcinoma. Prompted early external nasopharyngeal irradiation with endovascular treatment, can reduce the dose of external radiation (reduce radiation injury); Chinese medicine does not increase the distant metastasis, but can ease the adverse reactions