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目的探讨肝源性糖尿病的临床特点及治疗。方法观察45例肝硬化合并肝源性糖尿病患者的临床表现,检测治疗前、治疗后的血糖情况并进行比较分析。结果肝源性糖尿病患者以肝病表现为主,血糖波动较大,以餐后2h血糖升高为主;而Child-pugh分级C级患者的血糖明显高于A、B级患者,有并发症的患者血糖明显高于无并发症的患者。结论肝硬化患者易发生糖代谢紊乱,血糖水平与肝功能情况密切相关,经早期积极治疗,血糖基本可降至理想范围并稳定。
Objective To investigate the clinical features and treatment of liver-derived diabetes. Methods The clinical manifestations of 45 patients with liver cirrhosis and liver-derived diabetes mellitus were observed. The blood glucose levels before and after treatment were measured and compared. Results Hepatic disease was predominant in patients with liver-derived diabetes, and the fluctuation of blood glucose was large, with the increase of blood sugar at 2h after meal. The blood sugar of Child-pugh C patients was significantly higher than that of patients with A and B, with complications Patients with blood glucose was significantly higher than those without complications. Conclusions Patients with liver cirrhosis are prone to disorder of glucose metabolism. The blood glucose level is closely related to liver function. After active treatment in early stage, blood glucose can be reduced to the ideal range and stabilized.