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背景目前壶腹癌TNM分期系统的淋巴结分期仅区分淋巴结阴性(N0)和淋巴结阳性(N1),然而,有研究表明,淋巴结转移数目也是壶腹癌预后影响因素。淋巴结转移数目的预后判断价值已经被其他肿瘤证实并被应用于TNM分期系统,如食道癌,胃癌,结直肠癌和乳腺癌。2014年,Kang等提出了壶腹部癌淋巴结分类新方法:N0:区域淋巴结无转移;N1:1~2个区域淋巴结有转移;N2:3个(含)以上区域淋巴
Background Currently, the TNM staging system of ampullary carcinoma only differentiates between node-negative (N0) and node-positive (N1) lymph nodes, however, some studies have shown that the number of lymph node metastases is also the prognostic factor of ampullary carcinoma. The prognostic value of the number of lymph node metastases has been demonstrated by other tumors and has been used in TNM staging systems such as esophageal cancer, gastric cancer, colorectal cancer and breast cancer. In 2014, Kang et al proposed a new method for classification of lymph nodes in ampullary carcinoma: N0: no lymph node metastasis; N1: lymph node metastasis in 1-2 areas; N2: more than 3 lymph nodes