论文部分内容阅读
目的对1201例临床上拟诊为可疑脑膜炎的患儿抽取脑脊液(CSF)进行检测,分析CSF理化性质变化和病原菌感染情况。方法按常规临床检验方法对患儿CSF进行理化性质检测 ,同时采用国际标准方法对CSF进行致病菌培养、分离与鉴定。结果1201名患儿中CSF外观混浊者占9.33 %(112/1201) ,白细胞异常者占5.50 %(66/1201) ,糖、蛋白生化有1项或2项均异常者占23.06 %(277/1201) ;从1201份CSF中检出23株病原菌 ,其中理化性质正常的CSF检出率为l.01 %(9/892) ,外观混浊的CSF检出率为l.79 %(2/112) ,白细胞异常的CSF检出率为7.58 %(5/66) ,CSF生化异常的患儿检出7株病原菌 ,检出率为2.53 %(7/277)。结论CSF有异常改变的患儿病原菌检出率明显高于CSF正常的患儿 ,表明CSF异常者感染的危险性增加 ;患儿在发病初期CSF正常者也能检出病原菌 ,要引起临床工作者的高度重视 ,避免漏诊和误诊情况发生
Objective To detect cerebrospinal fluid (CSF) in 1201 children suspected to be suspected meningitis and analyze the changes of physical and chemical properties of CSF and pathogen infection. Methods The physical and chemical properties of CSF in children were tested according to the routine clinical test methods. At the same time, CSF was cultured, isolated and identified by international standard methods. Results Among 1201 children, turbidity of CSF was 9.33% (112/1201), abnormal leukocyte was 5.50% (66/1201), abnormal glucose and protein biochemistry was 23.06% (27.06% 1201). 23 pathogenic bacteria were detected from 1201 CSF, of which the detection rate of normal physiochemical CSF was l.01% (9/892) and the appearance of turbid CSF was 1.79% (2/112 ). The detection rate of leukocyte abnormal CSF was 7.58% (5/66). Seven pathogenic bacteria were detected in children with biochemical abnormalities of CSF. The detection rate was 2.53% (7/277). Conclusions The detection rate of pathogenic bacteria in children with abnormal CSF changes is significantly higher than that in normal CSF patients, indicating that the risk of infection is increased in patients with abnormal CSF. Children with normal CSF can also detect pathogens in the early stages of onset, The high degree of attention, to avoid misdiagnosis and misdiagnosis