Transplantation of human amniotic epithelial cells repairs brachial plexus injury:pathological and b

• 作 者: Qi Yang Min Luo Peng Li Hai Jin
• 机 构: China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China“,”Department of Mec
• 出 处: 中国神经再生研究（英文版）
• 发表日期: 2014年24期
• 关键词: nerve regeneration peripheral nerve injury brachial plexus injury animal model h

A brachial plexus injury model was established in rabbits by stretching the C6 nerve root. Imme-diately after the stretching, a suspension of human amniotic epithelial cells was injected into the injured brachial plexus. The results of tensile mechanical testing of the brachial plexus showed that the tensile elastic limit strain, elastic limit stress, maximum stress, and maximum strain of the injured brachial plexuses were signiifcantly increased at 24 weeks after the injection. The treat-ment clearly improved the pathological morphology of the injured brachial plexus nerve, as seen by hematoxylin eosin staining, and the functions of the rabbit forepaw were restored. These data indicate that the injection of human amniotic epithelial cells contributed to the repair of brachial plexus injury, and that this technique may transform into current clinical treatment strategies.