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血浆纤溶酶原激活物抑制物 1(ｐｌａｓｍｉｎｏｇｅｎａｃｔｉｖａｔｏｒｉｎｈｉｂｉ ｔｏｒｏｎｅ,ＰＡＩ 1)是纤溶系统的主要生理抑制剂 ,属于丝氨酸蛋白酶抑制剂超家族 ,可与组织型和尿激酶型纤溶酶原激活物(ｔ ＰＡ和ｕ ＰＡ)特异性结合 ,使二者迅速失活 ,从而发挥抗纤溶
Plasminogen activator inhibitor (PAI 1) is a major physiological inhibitor of the fibrinolytic system and belongs to the serine protease inhibitor superfamily, which interacts with tissue type and urokinase-type plasminogen activator t PA and u PA) specifically, so that both rapidly inactivated, which play anti-fibrinolytic