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目的对早期乳腺癌采用保留乳房的手术治疗配以术后放疗 ,以探讨其手术适应证和疗效。方法对 2 5例早期乳腺癌进行保乳手术并与传统根治术进行比较 ,保乳手术指征包括 :肿瘤直径小于 3cm ,腋窝淋巴结N0 或N1a肿瘤距乳头距离大于 3cm ,手术前乳腺照相排除多发癌灶。手术时肿瘤周围边界至少 2cm(冰冻切片证实 ) ,腋窝淋巴结解剖到第 2站 ,术后 2周内做放疗。从生存质量 (Qualityoflife ,QOL)的观点出发 ,分析保乳手术的适应证及存在的问题。结果两组术后均获随访 ,平均随访时间 6 4 1个月 ,保乳手术和传统根治术在 5年生存率和复发率的比较差异无显著意义(P >0 0 5 )。结论早期乳腺癌采用保乳手术治疗效果满意
Objective To use breast-conserving surgery combined with postoperative radiotherapy for early breast cancer to explore its indications for surgery and efficacy. Methods Twenty-five cases of breast cancer were treated with conservative surgery and compared with conventional radical mastectomy. The indications of breast-conserving surgery included tumor diameter less than 3 cm, axillary lymph node N0 or N1a distance greater than 3 cm from the papilla, Foci. Surgical boundary of the tumor at least 2cm (frozen section confirmed), axillary lymph nodes dissected to the second station, radiotherapy within 2 weeks after surgery. From the quality of life (Qualityoflife, QOL) point of view, analysis of breast conserving surgery indications and problems. Results Both groups were followed up for a mean of 641 months. There was no significant difference in 5-year survival rate and recurrence between breast-conserving surgery and radical mastectomy (P> 0.05). Conclusion Breast-conserving surgery in early breast cancer is satisfactory