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现行的英国肌注炭疽疫苗和美国皮下注射的吸附炭疽疫苗 ( AVA)都需多次接种才能获得恒定的保护性免疫。试验表明疫苗抗原微球化的优点多于传统疫苗配方。作者以小鼠为模型测定了将重组炭疽杆菌保护性抗原 ( r PA)制成微球进行免疫的效果。 将 r PA按一定程序包入分子量为1 0
The current British anthrax vaccine and the American subcutaneous injection of anthrax vaccine (AVA) require multiple inoculations to achieve constant protective immunity. Trials have shown that vaccine antigens have more advantages than traditional vaccine formulations. The authors used mouse as a model to determine the effect of recombinant Bacillus anthracis protective antigen (rPA) microspheres for immunization. The r PA is packaged into a program with a molecular weight of 10