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目的:探究甲状腺功能亢进症患者的血、尿β2-微球蛋白水平变化情况。方法:选取甲状腺功能亢进症患者34例作为研究组,另选同期来院体检健康者34例作为对照组,分别检测治疗前后两组患者血、尿β2-微球蛋白水平变化情况。结果:治疗前,研究组患者血、尿β2-微球蛋白水平均高于对照组(P<0.05)。研究组患者治疗后血、尿β2-微球蛋白水平与治疗前相比均显著降低(P<0.05)。结论:甲状腺功能亢进症患者血、尿β2-微球蛋白水平较正常水平高,这两种指标可准确反应患者病情变化,对患者临床疗效的判定具有重要的积极意义。
Objective: To investigate the changes of blood and urine β2-microglobulin levels in patients with hyperthyroidism. Methods: Thirty-four patients with hyperthyroidism were selected as the study group, and 34 healthy subjects were selected as the control group during the same period. The blood and urine β2-microglobulin levels were measured before and after treatment. Results: Before treatment, the levels of blood and urine β2-microglobulin in study group were higher than those in control group (P <0.05). After treatment, the levels of blood and urine β2-microglobulin in study group were significantly lower than those before treatment (P <0.05). CONCLUSION: Blood and urinary β2-microglobulin levels in patients with hyperthyroidism are higher than normal. These two indicators can accurately reflect the changes of patients’ condition, and have an important and positive effect on the determination of clinical efficacy.