论文部分内容阅读
目的探讨外周血癌胚抗原(CEA)水平与胆囊癌预后的相关性。方法回顾性分析2006年1月至2013年6月间收治的76例胆囊癌患者,行肝胰十二指肠切除术后,测定其外周血CEA水平,CEA>8.95μg/L为A组,CEA≤8.95μg/L为B组。随访记录两组患者的复发情况和生存时间,分析其与外周血CEA水平的关系。结果 76例患者外周血CEA水平为(8.98±1.27)μg/L,中位数为8.95μg/L。其中A组外周血CEA水平为(11.21±2.43)μg/L,B组外周血CEA水平为(7.13±1.85)μg/L,两组差异有统计学意义(P<0.05)。A组患者的生存时间为(82.16±48.32)周,B组为(191.88±111.84)周,两组差异有统计学意义(P<0.05)。A组患者复发21例,B组复发7例,A组复发患者明显多于B组(P<0.05)。结论胆囊癌患者外周血CEA水平较高者预后较差。
Objective To investigate the correlation between the level of CEA in peripheral blood and the prognosis of gallbladder cancer. Methods A retrospective analysis of 76 patients with gallbladder carcinoma admitted between January 2006 and June 2013 was performed. Hepatectomy and duodenal resection were performed to determine the level of CEA in peripheral blood. CEA> 8.95μg / L was given as group A, CEA≤8.95μg / L for the B group. Follow-up records of the two groups of patients relapse and survival time, analysis of the relationship with peripheral blood CEA levels. Results The CEA level in peripheral blood was (8.98 ± 1.27) μg / L in 76 patients with a median of 8.95 μg / L. The level of CEA in peripheral blood of group A was (11.21 ± 2.43) μg / L and that of group B was (7.13 ± 1.85) μg / L, the difference was statistically significant (P <0.05). The survival time of group A was (82.16 ± 48.32) weeks, while that of group B was (191.88 ± 111.84) weeks. There was significant difference between the two groups (P <0.05). In group A, 21 patients relapsed and 7 patients relapsed in group B. The recurrences in group A were more than those in group B (P <0.05). Conclusion The prognosis of patients with gallbladder cancer with higher CEA levels is poor.