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目的 :进一步观察和评价头孢羟氨苄胶囊 (赛锋 )对急性呼吸道感染的临床有效性和安全性。方法 :选择急性呼吸道感染患者 60例 ,随机分成两组 ,分别给予头孢羟氨苄胶囊和头孢克洛口服治疗 ,从临床表现及实验室检验两方面对其疗效和安全性进行对比评价。结果 :头孢羟氨苄胶囊治疗急性呼吸道感染的临床有效率为 80 % ,痰分离致病菌的药敏率 89% ,细菌清除率为 84 % ,头孢克洛则分别为 73 % ,82 % ,74 % ,差异均无显著性 ( P>0 .0 5 )。前者不良反应的发生率 ( 6% )较后者 ( 17% )低。结论 :头孢羟氨苄是一种有效而安全的治疗呼吸道轻中度急性感染的口服抗生素
Objective: To further observe and evaluate the clinical efficacy and safety of cefadroxil capsules (Saifeng) in acute respiratory infections. Methods: Sixty patients with acute respiratory infection were selected and randomly divided into two groups. Patients were treated with cefadroxil capsules and cefaclor orally, respectively. The curative effect and safety of the two groups were compared and evaluated from clinical manifestations and laboratory tests. Results: The clinical effective rate of cefadroxil capsule for acute respiratory infection was 80%, the drug sensitivity of sputum isolated bacteria was 89%, bacterial clearance rate was 84% and cefaclor 73%, 82%, 74 %, No significant difference (P> 0.05). The former had a lower incidence of adverse reactions (6%) than the latter (17%). Conclusion: Cefadroxil is an effective and safe oral antibiotic for mild to moderate acute respiratory infections