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目的：评估生长抑素（施他宁，ｓｔｉｌａｍｉｎ）对急性水肿型胰腺炎（ＡＥＰ）的治疗价值及应用指征。方法：用回顾性分析方法，将１６３例ＡＥＰ按年龄及有否加用生长抑素分为４组。按下列指标评估：腹痛消失时间、血淀粉酶复常时间、转为急性重症胰腺炎（ＡＮＰ）发生率、手术率、病死率。结果：大于５５岁的两组，腹痛消失时间生长抑素治疗组（治疗组）为（２．５±１．７）天；无生长抑素组（对照组）为（４．９±２．２）天，Ｐ＜０．０５；血淀粉酶复常时间治疗组为（３．２±１．８）天；对照组为（４．８±２．８）天，Ｐ＜０．０５；转为ＡＮＰ的发生率，治疗组为８％（３／４０）；对照组为２３％（７／３１），Ｐ＞０．０５；转手术率，治疗组为５％（２／４０）；对照组为１６％（５／３１），Ｐ＞０．０５。小于或等于５５岁的两组，腹痛消失时间和血淀粉酶复常时间均无统计学差别。结论：ＡＥＰ高龄患者早期应用生长抑素治疗，能缩短病程，改善预后。
Objective: To evaluate the therapeutic value of stilamin in patients with acute edematous pancreatitis (AEP) and its application indications. Methods: A retrospective analysis of 163 cases of AEP by age and whether or not with somatostatin divided into 4 groups. According to the following indicators to assess: the disappearance of abdominal pain, blood amylase time to normal, severe acute pancreatitis (ANP) incidence, operation rate, mortality. Results: In the two groups of more than 55 years old, the disappearance of abdominal pain was (2.5 ± 1.7) days in the somatostatin treatment group and 4.9 ± 2 days in the non-somatostatin treatment group (control group). 2) days, P <0.05; the duration of serum amylase time was (3.2 ± 1.8) days in treatment group and (4.8 ± 2.8) days in control group, P <0.05; The incidence of ANP was 8% (3/40) in the treatment group and 23% (7/31) in the control group, P> 0.05. The rate of the operation was 5% (2/40) in the treatment group. The control group was 16% (5/31), P> 0.05. There were no significant differences between the two groups less than or equal to 55 years old, the disappearance of abdominal pain and the time of serum amylase recovery. Conclusion: AEP patients with early treatment of somatostatin can shorten the course of disease and improve prognosis.