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目的:探讨保尔佳(Polyerga)减轻癌症病人化疗副反应临床疗效。方法:用随机、双盲法对55例胃肠肿瘤病人于癌肿根治术后,分为试验组(28例)和对照组(27例),在常规化疗的同时,前者给予保尔佳,后者给予安慰剂,治疗前后观察患者一般状况、血液学和免疫学等指标的变化。结果:保尔佳能明显缓解化疗引起的恶心呕吐反应,增进食欲,改善贫血,增加体重;对免疫功能也有一定激活作用;以Karnofsky指数评价健康状况,试验组改善明显。结论:保尔佳能明显减轻化疗副反应。
Objective: To investigate the clinical efficacy of Polyerga in the reduction of chemotherapy side effects in cancer patients. METHODS: Randomized, double-blind method was used to treat 55 patients with gastrointestinal cancer after radical surgery for cancer. The patients were divided into experimental group (28 cases) and control group (27 cases). The latter gave a placebo, and the changes in general conditions, hematology, and immunology were observed before and after treatment. RESULTS: Pall can significantly relieve chemotherapy-induced nausea and vomiting, increase appetite, improve anemia, and increase body weight. It also has certain activation effect on immune function. The Karnofsky index was used to evaluate the health status of the experimental group. Conclusion: Paul Canon significantly reduced chemotherapy side effects.