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介绍了微囊藻毒素(MCs)和结球藻毒素(NOD)的结构与毒性。相比于其他方法,在检测肽类藻毒素的应用上,液质联用法(LC-MS)具有操作简单,检测限低,可有效分析组分结构等优点。对检测过程中提取、纯化、分离和检测等重要步骤的适合条件和方法特点以及质谱检测方法前景进行了评述。
The structure and toxicity of microcystins (MCs) and nodulalins (NOD) are introduced. Compared with other methods, liquid chromatography-mass spectrometry (LC-MS) has the advantages of simple operation, low detection limit and effective analysis of the structure of the components in the detection of peptide algal toxins. The suitable conditions and methods of extraction, purification, separation and detection during the detection process, as well as the prospect of mass spectrometry were reviewed.