论文部分内容阅读
目的探讨急性呼吸综合症(ARDS)患者死亡的危险因素。方法回顾性分析2012年1月至2013年12月收治的250例ARDS患者的临床资料,根据患者预后情况将其分为存活组(n=155例)以及死亡组(n=95例),对比分析两组患者临床资料,并对于影响患预后的危险因素进行Logisitic多因素回归分析。结果经单因素分析可知,死亡组患年龄高于存活组,外肺水指数(EVLWI)、器官功能障碍评分(SOFA)评分、急性生理及慢性健康评分Ⅱ(APACHE Ⅱ评分)、肺损伤评分(Murray)评分、动脉血氧分压(PaO2)、平均脉压(MAP)、脓毒症发生率、器官不全比例显著高于存活组,差异有统计学意义(P<0.05)。经Logistic多因素回归分析可知,EVLWI、SOFA评分、APACHE Ⅱ评分、Murray评分、脓毒症发生率是影响ARDS患者预后的独立危险因素。结论 ARDS临床死亡率高,EVLWI、SOFA评分、APACHE Ⅱ评分、Murray评分、PaO2、脓毒症发生率是影响ARDS患者预后的独立危险因素。对影响ARDS患者预后的危险因素进行分析可为临床进行针对性的治疗提供指导。
Objective To investigate the risk factors of death in patients with acute respiratory syndrome (ARDS). Methods The clinical data of 250 patients with ARDS admitted from January 2012 to December 2013 were retrospectively analyzed. According to their prognosis, they were divided into survival group (n = 155) and death group (n = 95) The clinical data of two groups were analyzed, and the risk factors influencing the prognosis were analyzed by Logistic regression analysis. Results According to univariate analysis, the age of death group was higher than that of survival group, EVLWI, SOFA score, acute physiology and chronic health score Ⅱ (APACHE Ⅱ score), lung injury score ( Murray score, arterial oxygen pressure (PaO2), mean pulse pressure (MAP), the incidence of sepsis, organ failure were significantly higher than the survival group, the difference was statistically significant (P <0.05). Logistic regression analysis showed that the EVLWI, SOFA score, APACHE Ⅱ score, Murray score and the incidence of sepsis were independent risk factors for the prognosis of patients with ARDS. Conclusion The ARDS clinical mortality rate, EVLWI, SOFA score, APACHE Ⅱ score, Murray score, PaO2, the incidence of sepsis are independent risk factors affecting the prognosis of patients with ARDS. Analysis of the risk factors affecting the prognosis of patients with ARDS can provide guidance for targeted treatment in clinical practice.