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白癜风的发病学,现代倾向于与免疫介导的黑素细胞破坏有关。支持此种理论的证据包括本病常伴有其它自身免疫性疾病;血行中存在器官特异性自身抗体;证明有抗黑素细胞抗体及皮损部位基底膜带有IgG及C_3的沉积。本文对20例白癜风患者及16名健康对照者作了研究,应用间接免疫荧光法及补体介导细胞毒性试验测定周围血总T细胞(OKT_3)、辅助性T细胞(O
The pathogenesis of vitiligo, modern tend to be associated with immune-mediated destruction of melanocytes. Evidence supporting this theory includes the presence of other autoimmune diseases in this disease; presence of organ-specific autoantibodies in the bloodstream; evidence of anti-melanocyte antibodies and deposition of IgG and C 3 in the basement membrane of the lesions. In this paper, 20 cases of vitiligo patients and 16 healthy controls were studied. Indirect immunofluorescence and complement-mediated cytotoxicity assays were used to measure the levels of OKT 3,