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目的该文通过对246例不能切除之Ⅲ期非小细胞肺癌进行放射治疗合并口服平消胶囊与单纯放射治疗对比研究,评价放射治疗合并平消胶囊综合治疗的价值。材料与方法所有病人均经病理确诊。综合治疗组122例,采用高能X线或~(60)Co-r线放疗,肺原发灶D_T60~70Gy,放疗期间口服平消胶囊。单纯放疗组124例,放射治疗方法同综合治疗组。结果综合治疗组有效率稍高于单纯放疗组,但无统计学差异。综合治疗组生存率似乎高于单纯放射治疗组,中位生存期延长2个月(P值接近0.05)。综合治疗组放射性肺损伤的发生率明显低于单纯放射治疗组,且白细胞减少的机率降低,明显提高了生存质量。结论平消胶囊合并放射治疗能明显提高生存质量。
Objective To evaluate the value of radiotherapy combined with Pingxiao Capsule in the treatment of 246 cases of unresectable stage III non-small cell lung cancer by radiotherapy combined with oral Pingxiao capsule and radiotherapy alone. Materials and Methods All patients were confirmed by pathology. In the comprehensive treatment group, 122 patients were treated with high-energy X-ray or ~(60)Co-r line radiotherapy. The primary lung lesions were D_T60 ~ 70Gy, and oral Pingxiao capsules during radiotherapy. In the radiotherapy alone group, 124 cases were treated with radiotherapy. Results The effective rate of the comprehensive treatment group was slightly higher than that of the single radiotherapy group, but there was no statistical difference. The overall survival rate of the combined treatment group appeared to be higher than that of the radiotherapy alone group, and the median survival time was prolonged by 2 months (P value was close to 0.05). The incidence of radiation-induced lung injury in the comprehensive treatment group was significantly lower than that of the radiotherapy alone group, and the probability of leukopenia decreased, which significantly improved the quality of life. Conclusion Pingxiao capsule combined with radiation therapy can significantly improve the quality of life.