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东南亚和西太平洋地区报道过间日疟原虫对氯喹(CQ)产生耐药性。经正规的抗疟治疗后仍有原虫血症,表明存在耐药的情况。但因缺乏对耐药的诊断标准,这类报道为数不多。为了进一步建立间日疟原虫对CQ耐药的诊断标准,作者以91名印度尼西亚疟疾患者为研究对象,并结合前人的早期临床资料进行了有关的分析研究。 早期临床资料报道,333名间日疟原虫感染的患者经正规奎宁治疗(共14天),治疗中均无复发,半数复发天数为23天,至第30
Southeast Asia and the Western Pacific reported that P. vivax is resistant to chloroquine (CQ). After the formal anti-malaria treatment still parasitemia, indicating the presence of resistance. However, due to the lack of diagnostic criteria for drug resistance, such reports are few. In order to further establish the diagnostic criteria of Plasmodium vivax for CQ resistance, the author studied 91 malaria patients in Indonesia and combined with the previous clinical data. Early clinical data reported that 333 patients with Plasmodium vivax infection were treated with formal quinine for a total of 14 days. There was no recurrence during treatment, with a median of 23 days recurrence to day 30