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目的:对糖尿病足患者采取盐酸川芎嗪注射液联合前列地尔治疗的临床效果进行分析探究。方法:选取2012年1月—2016年1月本院收治的糖尿病足患者86例,按照随机分配原则,平分为对照组与观察组,各43例。对照组采用盐酸川芎嗪注射液进行治疗,观察组采用盐酸川芎嗪注射液联合前列地尔进行治疗。对比两组患者治疗后的神经传导速度及临床治疗效果。结果:经治疗后,对照组的治疗总有效率为79.07%,观察组的治疗总有效率为90.70%,观察组优于对照组,差异具有统计学意义(P<0.05);同时在运动神经传导速度(MCV)评分及感觉神经传导速度(SCV)评分上,观察组均高于对照组,血流速度低于对照组,差异具有统计学意义(P<0.05)。结论:糖尿病足采取盐酸川芎嗪注射液联合前列地尔进行治疗的临床效果显著,可有效提高患者的神经传导速度,值得推广应用。
Objective: To investigate the clinical effect of ligustrazine hydrochloride injection combined with alprostadil in patients with diabetic foot. Methods: Totally 86 diabetic foot patients admitted in our hospital from January 2012 to January 2016 were selected and divided into control group and observation group according to the principle of random distribution, 43 cases in each group. The control group was treated with Ligustrazine Hydrochloride Injection. The observation group was treated with Ligustrazine Hydrochloride Injection and Alprostadil. The nerve conduction velocity and clinical effect of the two groups were compared after treatment. Results: After treatment, the total effective rate of the control group was 79.07%, the total effective rate of the observation group was 90.70%, the observation group was superior to the control group, the difference was statistically significant (P <0.05); while in the motor nerve The MCV score and SCV score of the observation group were higher than those of the control group, and the blood flow velocity was lower than that of the control group. The difference was statistically significant (P <0.05). Conclusion: The clinical effect of taking tetramethylpyrazine hydrochloride injection combined with alprostadil for the treatment of diabetic foot is significant, which can effectively improve the nerve conduction velocity in patients and is worth popularizing and applying.