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从槐属植物Sophoraexigua干燥根中分离出一种黄酮化合物,经结构鉴定为5,7,2’,4’-四羟基-8-熏衣草烷基-二氢黄酮(THLF)。本文研究了THLF和5种抗菌素对新青霉素Ⅰ(DMPPC)耐药菌株金黄色葡萄球菌(MRSA)的抗菌活性及与抗MRSA类药物的协同作用。结果表明:1)21株MRSA中
A flavonoid compound was isolated from the dried roots of the genus Sophora exigua and was identified by structure as 5,7,2’,4’-tetrahydroxy-8- lavenderyl-dihydroflavone (THLF). This paper studied the antibacterial activity of THLF and five antibiotics against neo-penicillin I (DMPPC)-resistant strain of Staphylococcus aureus (MRSA) and its synergy with anti-MRSA drugs. The results showed that: 1) 21 strains of MRSA