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所谓“药原性疾病”是指在临床用药过程中,因药物或药物之间的相互作用所引起的与治疗目的无关的不良反应,以及由此而导致某些器官或局部组织产生功能性或器质性损害而出现的各种临床症状和疾病。但是,一般不包括药物极量所引起的急性中毒。一、药原性疾病的易感因素与发生原因药物遗传学研究证实,具有不同遗传素质的人对药源性疾病的易感性并不一样,其中有遗传缺陷的人易于在接受药物时发生常人并不一定发生的药性疾病或不良反应。例如:葡萄糖-6-磷酸脱氢酶
The so-called “drug-induced diseases” refers to the clinical medication, due to drug or drug interactions caused by unrelated to the purpose of the adverse reactions, and thus resulting in some organs or local tissue to produce functional or Organic damage and the emergence of a variety of clinical symptoms and diseases. However, acute poisoning caused by extremely large doses of drugs is generally not included. First, susceptibility factors and causes of drug-induced diseases Pharmacogenetics studies have confirmed that people with different genetic predisposition to drug-induced disease is not the same, including genetic defects in people prone to occur when people often accept drugs It does not necessarily occur as a medical illness or adverse reaction. For example: glucose-6-phosphate dehydrogenase