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应用放免分析法检测６０例前列腺增生症（ＢＰＨ）患者的血、尿β２－微球蛋白（β２－Ｍ）及血尿素氮（ＢＵＮ）和肌酐（Ｃｒ）水平，发现β２－Ｍ与残余尿量呈高度正相关；尤以尿值升高明显，残余尿量＞１００ｍｌ时，与对照组有显著性差异，伴肾积水者血、尿β２－Ｍ均明显升高，ＢＵＮ和Ｃｒ与对照组均无显著差异。表明：检测β２－Ｍ有利于早期发现肾功能的损害程度，且灵敏度明显高于血ＢＵＮ和Ｃｒ。
Radioimmunoassay was used to detect the levels of blood and urine β2-microglobulin (BUN) and serum creatinine (BUN) and blood creatinine (BUN) in 60 patients with benign prostatic hyperplasia (BPH) With a high degree of positive correlation; especially in the urine value increased significantly, residual urine output> 100ml, with the control group were significantly different, with hydronephrosis blood and urine β2-M were significantly increased, BUN and Cr and control group No significant difference. It is indicated that the detection of β2-M is beneficial to the early detection of renal damage and the sensitivity is significantly higher than that of blood BUN and Cr.