论文部分内容阅读
近年来,头发与微量元素的关系受到营养学、职业病学和环境科学工作者的重视。头发作为活检材料的优点主要是:采样时无疼痛和创伤;样品易于贮存和运送,不需特殊设备;不易变质,可长期保存,于必要时再进行检验;很多微量元素在毛发中浓度较高,故可简化分析工作;特别是,头发犹如录音带,能反映过去某时期微量元素的摄入和代谢的历史,这是其他生物材料所无法比拟的。头发是蛋白质组织,代谢活性极低,是代谢的终末产物,可以把毛囊看作为微小的微量元素排泄器官。已知砷、铅、汞、硒、铋等元素在毛囊与巯基、氨基等结合进入角蛋白分子,但目前对于毛发排泄微量元素的机制还很不清楚。表1列出了人发化学组成及微量元素
In recent years, the relationship between hair and trace elements is valued by nutritionists, occupational medicine and environmental scientists. The advantages of hair as a biopsy material are: no pain and trauma when sampling; easy storage and transport of samples without special equipment; non-perishable, long-term storage and retesting if necessary; many trace elements are highly concentrated in hair , So the analysis can be simplified. In particular, the hair is like a tape that reflects the past history of trace element ingestion and metabolism, which is unmatched by other biological materials. Hair is a protein tissue, metabolic activity is very low, is the metabolic end products, hair follicles can be seen as a tiny excretion of trace elements. Known arsenic, lead, mercury, selenium, bismuth and other elements in the hair follicles and mercapto, amino and other incorporated into the keratin molecules, but the mechanism of the hair excretion of trace elements is still not clear. Table 1 lists the human hair chemical composition and trace elements