论文部分内容阅读
目的:分析儿童重症肺炎支原体肺炎(MPP)的临床特征,为临床诊治提供参考依据。方法:对我院2015年1月至2016年12月住院治疗的152例MPP患儿的临床资料进行回顾性分析。结果:重症组以学龄前期儿童为主,年龄较普通组小,两组年龄构成比较差异有统计学意义(P<0.05)。重症组发热、咳嗽及住院时间较普通组长(P<0.05),气急发生率、肺部体征阳性率、炎性指标增高比例均大于普通组(P<0.05)。有26例(48.1%)重症组患儿出现肺外并发症,以肝功能损害最常见。重症组激素和静脉丙种球蛋白使用率均大于普通组(P<0.05)。29例(53.7%)重症组患儿进行了电子支气管镜肺泡灌洗术。两组患儿治疗有效率比较差异无统计学意义(P>0.05)。结论:肺炎支原体感染后小龄儿童更易发展为重症MPP,重症MPP临床症状重,肺部炎症明显,易合并肺内外并发症,经抗感染、免疫支持、支气管镜肺泡灌洗术治疗,预后良好。
Objective: To analyze the clinical features of children with severe Mycoplasma pneumoniae pneumonia (MPP) and provide a reference for clinical diagnosis and treatment. Methods: The clinical data of 152 MPP children admitted to our hospital from January 2015 to December 2016 were analyzed retrospectively. Results: The severe group was predominately preschool children with younger age than the normal group. There was significant difference in age constitution between the two groups (P <0.05). The incidences of fever, cough and hospital stay in the severe group were significantly higher than those in the normal group (P <0.05). The incidence of shortness of breath, the positive rate of lung signs and the increase of inflammatory indexes in the severe group were higher than those in the normal group (P <0.05). In 26 cases (48.1%) severe group of children with extrapulmonary complications, the most common liver damage. Severe group of intravenous hormone and intravenous gamma globulin use rates were higher than the normal group (P <0.05). Twenty-nine patients (53.7%) underwent severe bronchoscopic bronchoalveolar lavage. There was no significant difference in the treatment efficiency between the two groups (P> 0.05). Conclusions: Mycoplasma pneumoniae is more likely to develop severe MPP after infection with Mycoplasma pneumoniae. Clinical symptoms of MPP are severe, pulmonary inflammation is obvious, complicated with complicated pulmonary complications. After anti-infection, immune support and bronchoscopic alveolar lavage, the prognosis is good .