论文部分内容阅读
目的 观察治疗性血小板单采术对原发性血小板增多症 (essentialthrombocythemia ,ET)患者的疗效。方法 应用HeamoncticsMCS +全自动细胞分离机对 3例ET患者行治疗性血小板单采术。每例患者行 3次治疗性血小板单采术 ,每次采集 8个循环 ,采集成品血小板 2 34ml。术中留取血样复查血小板计数。结果 3例患者经3次治疗性血小板单采术后血小板计数降至正常水平 ;同时口服羟基脲 (0 .5 g ,每日 2次 )。 1周后症状消失出院 ,随访 6个月 ,复查血小板计数在正常范围内。结论 ET患者应用治疗性血小板单采术能迅速降低血小板计数 ,同时口服羟基脲治疗有利于巩固临床疗效
Objective To observe the curative effect of therapeutic platelet apheresis on patients with essential thrombocythemia (ET). Methods Three patients with ET were treated with HeamoncticsMCS + automatic cell separator for the treatment of thrombocytopenia. Each patient was treated 3 times with therapeutic platelets apheresis, each collecting 8 cycles, collecting the finished platelet 2 34ml. Intraoperative blood samples were taken for review of platelet counts. Results The platelet count of 3 patients dropped to normal level after 3 times of therapeutic platelet apheresis. At the same time, hydroxyurea was orally taken (0.5 g twice daily). Symptoms disappeared 1 week after discharge, follow-up 6 months, review platelet count within the normal range. Conclusion ET patients using therapeutic platelets apheresis can rapidly reduce platelet count, while oral hydroxyurea treatment is conducive to consolidate the clinical efficacy