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目的：观察剖宫产及硬膜外吗啡术后镇痛产妇的泌乳状况及血清泌乳素（ＰＲＬ）变化。方法：足月初产妇１２０例均分为四组：Ⅰ组术毕行硬膜外吗啡镇痛；Ⅱ组术毕硬膜外吗啡镇痛，２４小时后追加１次；Ⅲ组未行术后镇痛；阴道自然分娩３０例为Ⅳ组。结果：产后５分钟、２４及４８小时ＰＲＬ值变化各组间无显著性差异。Ⅳ组产后２４小时内开始泌乳发生率（４０％），高于同期所有剖宫产组（２０％）；但４８小时内开始泌乳及７２小时乳汁分泌不足发生率与剖宫产组相比无差异。剖宫产三组平均术后镇痛时间明显不同，但各组产妇开始泌乳及乳汁分泌不足发生率均无差异。结论：剖宫产及硬膜外吗啡术后镇痛不影响产妇母乳喂养的成功率。
Objective: To observe the lactation status and serum prolactin (PRL) changes of cesarean section and epidural morphine postoperative analgesia. Methods: 120 full-term primipara were divided into four groups: group Ⅰ epidural morphine analgesic; epidural morphine analgesia in group Ⅱ, additional 1 after 24 hours; group Ⅲ without post-operation Pain; vaginal natural childbirth 30 cases for the group Ⅳ. Results: There was no significant difference in PRL value between 5 and 12 months after birth in 24 and 48 hours. In group Ⅳ, the incidence of lactation (40%) was higher than that in cesarean section (40%) within 24 hours after delivery, but the incidence of lactation within 48 hours and the rate of insufficient milk secretion within 72 hours difference. The mean postoperative analgesia time of the three groups of cesarean section was significantly different, but there was no difference in the incidence of lactation and insufficient milk secretion among the three groups. CONCLUSIONS: Cesarean and postoperative analgesia of epidural morphine did not affect the success rate of breastfeeding mothers.