THE NEED FOR ALTERNATIVE ASSAYS TO BACTERIAL GROWTH INHIBITION FOR THE CONTROL OF ANTITUMOUR ANTIBIO

• 作 者: John M. C. Gutteridge
• 机 构: Division of Antibiotics and Chemistry, National Institute for Biological Standards and Control, Lond
• 出 处: 抗生素
• 发表日期: 1984年06期
• 关键词: microbial toxicity simplicity antibiotics arise continued notable altered latter

Antitumour Antibiotics Antibacterial activity,in mose cases,led to the discovery and isolationof antitumour antibiotics although,becauseof their high toxicity,they areseldom considered for clinical treatmentof infections.Antibacterial propertieshave,however,continued to beused as the basis for their standardisationand control.The use of inhibitionof microbial growth by these drugs forthese purposes offers several advantagesof which relative simplicity,thepossibility of some level of automatonand the attainment of a high degreeof precision,are notable.An obviousquestion that must arise from such

Antitumour Antibiotics Antibacterial activity, in mose cases, led to the discovery and isolationof antitumor antibiotics although, becauseof their high toxicity, they areseldom considered for clinical treatmentof infections. An antibacterial activity, however, continued to beused as the basis for their standardization and control.The use of inhibition of microbial growth by these drugs forthese issues offers several advantages of which relative simplicity, thepossibility of some level of automaton and the attainment of a high degree of precision, are not able to .An obviousquestion that must arise from such