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摘要目的评估结节性硬化症(TSC)病人胸部CT影像上的心肌脂肪灶(MFF)与基因突变的类型或多器官受累之间的关系。材料与方法该回顾性病例对照研究获得了伦理委员会批准,并免除病人知情同意。48例明确诊断为TSC的病人[其中女性41例,平均年龄(35±11)岁]和96例年龄和性别相匹配的经过胸部CT评估没有患TSC的病人纳入本研究。2名CT阅片者独立地进行测量,将MFF定义为心肌内
Abstract Objective To evaluate the relationship between myocardial fat spot (MFF) in chest CT images of patients with tuberous sclerosis (TSC) and the type of gene mutation or multiple organ involvement. Materials and Methods The retrospective case-control study was approved by ethics committee and patient informed consent was waived. Forty-eight patients with definite diagnosis of TSC [41 women (mean age 35 ± 11) years] and 96 age- and sex-matched patients with TSC who underwent chest CT evaluation were enrolled in this study. Two CT readers independently measured MFF as intramyocardial