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以临床诊断明确为胰岛素非依赖型糖尿病(NIDDM,Ⅱ型)并有10年以上病史的患者为对象,研究控制血糖,调节体重的良否与血管合并症演变的关系。诊断后立即到我院初诊,经内科10年持续治疗的184例(男82例、女102例)的NIDDM患者,治疗5年而且以后体重调节保持在不到标准体重的110％者为体重调节组,其他为体重非调节组。年平均的空腹血糖(FPG)值超过150mg/dl的期间不到三年者为血糖控制良好组,三年以上者为血糖控制不良组。眼底检查最少进行一次眼底照相,并用超声波(多普勒法)检查下肢血流障碍。结果:1)诊断后一年内以50g口服葡萄糖耐量试验(O-GTT)检查血中胰岛素水平有随着肥
The clinical diagnosis of patients with insulin-independent diabetes mellitus (NIDDM, type II) and more than 10 years of history as the object, to study the relationship between the control of blood glucose, weight gain and the evolution of vascular complications. Immediately after diagnosis, 184 patients (82 males and 102 females) who underwent continuous medical treatment for 10 years were enrolled in our hospital. After 5 years of treatment and thereafter, the body weight was maintained at less than 110% of the standard body weight, Group, the other non-weight-adjusted group. Those with a mean fasting blood glucose (FPG) value of over 150 mg / dl for less than three years had a well-controlled glycemic control and those with more than three years had poor glycemic control. Fundus examination The fundus photography was performed at least once and the lower extremity blood flow disorder was examined by ultrasound (Doppler method). Results: 1) Within one year after diagnosis, the level of insulin in 50g oral glucose tolerance test (O-GTT)