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目的:探讨单侧肺循环阻断术治疗局部晚期非小细胞肺癌(LANSCLC)的临床应用价值。方法:选择30例行单侧肺循环阻断术的LANSCLC患者作为治疗组,随机选择行单纯肺动脉阻断术的患者30例作为对照组,比较2种手术方法在手术时间、术中出血量、动脉阻断时间、术后并发症方面的差异。结果:治疗组动脉阻断时间、手术时间明显短于对照组,治疗组术中出血量亦明显少于对照组,差异均有统计学意义(P<0.01)。2组术后并发症发生率为治疗组(6.7%)低于对照组(23.3%),但差异无统计学意义(P>0.05)。结论:单侧肺循环阻断术为治疗晚期LANSCLC的一种手术方法,缩短了手术时间、降低了出血量、减少了术后并发症,值得临床进一步推广研究。
Objective: To investigate the clinical value of unilateral pulmonary bypass in the treatment of locally advanced non-small cell lung cancer (LANSCLC). Methods: 30 patients with LANSCLC who underwent unilateral pulmonary blockade were selected as the treatment group. Thirty patients randomly selected for simple pulmonary artery occlusion were selected as the control group. The operation time, intraoperative blood loss, Blocking time, postoperative complications in terms of differences. Results: The arterial occlusion time and operation time in the treatment group were significantly shorter than those in the control group. The bleeding volume in the treatment group was also significantly less than that in the control group, with significant differences (P <0.01). The incidence of postoperative complications in the two groups was lower in the treatment group (6.7%) than in the control group (23.3%), but the difference was not statistically significant (P> 0.05). CONCLUSION: Unilateral pulmonary circulation occlusion is a surgical method for the treatment of advanced LANSCLC, which can shorten the operation time, reduce the amount of bleeding and reduce the postoperative complications, which deserves further clinical research.