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为探讨免疫功能紊乱与妊娠中毒症发病机理的关系,对40例妊娠中毒症患者采用白细胞游走抑制试验,测定其周围血白细胞对胎盘抗原和植物血凝素的反应性。结果显示妊娠中毒症患者对两种抗原的白细胞游走抑制率均明显高于正常孕妇(P<0.001),而且用胎盘抗原的结果更为明显。90%的病例对胎盘抗原呈阳性反应,而正常孕妇的阳性率仅30%,阳性反应患者的白细胞游走抑制率(34.4%)也明显较对照组(28.2%)
In order to investigate the relationship between immune dysfunction and the pathogenesis of gestosis, 40 patients with gestosis were tested for leukocyte migration to determine the reactivity of peripheral white blood cells to placental antigen and phytohemagglutinin. The results showed that patients with gestational toxicosis leukocyte migration inhibition rate of both antigens were significantly higher than the normal pregnant women (P <0.001), and the results with the placental antigen more obvious. 90% of cases positive for placental antigen, while the positive rate of normal pregnant women was only 30%, the positive reaction of leukocyte migration inhibition rate (34.4%) was significantly higher than the control group (28.2%)