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本文用过氧化物酶抗过氧化物酶(PAP)法,对87例子宫颈鳞状土皮癌、20例子宫颈腺癌及54例子宫内膜癌组织进行了癌胚抗原(CEA)的研究.通过病理形态学观察及统计学处理,探讨CEA与癌组织学变化、细胞学分化、临床分期等因素的关系.对癌组织内的CEA检测可应用于子宫颈鳞状上皮原位癌与不典型增生上皮,以及子宫颈腺癌与子宫内膜癌的鉴别诊断;对正常子宫颈鳞状上皮进行CEA检测,可用于筛选随访,观察早期子宫颈癌病例.提出癌细胞内CEA的表达(expression)程度可能与癌细胞的分化过程和分化程度有关.
In this study, carcinoembryonic antigen (CEA) was studied in 87 cases of cervical squamous carcinoma, 20 cases of cervical adenocarcinoma and 54 cases of endometrial carcinoma using peroxidase-peroxidase (PAP) method. The relationship between CEA and histological changes, cytological differentiation, clinical stage and other factors were studied by pathomorphological observation and statistical analysis.Cear CEA detection in cancerous tissues could be applied to cervical squamous carcinoma in situ and atypical Hyperplastic epithelium, and the differential diagnosis of cervical adenocarcinoma and endometrial cancer; CEA detection of normal cervical squamous epithelium can be used for screening follow-up to observe the early cases of cervical cancer .Can put forward the expression of CEA in cancer cells (expression) The extent may be related to the differentiation and differentiation of cancer cells.