OPTINEURIN SEQUENCE VARIANTS IN BRITISH GLAUCOMA SUBJECTS

• 作 者: T.Aung G.Brice
• 机 构: InstituteofOphthalmologyUniversityCollege,StGeorge&,#8217,SHospitalMedSchool
• 出 处: 国际眼科杂志
• 发表日期: 2003年1期
• 关键词: 青光眼 英国患者 OPTINEURIN 基因突变 POAG

<正> Aim: A recent study found that the Optineurin (OPTN) gene was mutated in families with primary open angle glaucoma (POAG), A misense mutation E50K was present in 13.5% of families studied, and the M98K risk-associated change was identified in 13