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目的应用~(99m)锝-二乙基三胺五乙酸(~(99m)Tc-DTPA)液体试餐进行核素胃排空显像,对前、后位动态影像进行比较,以期为临床甄选一个简便、准确的胃排空功能检查方法,并提供胃排空功能正常及异常的定量参考指标。方法口服~(99m)Tc-DTPA液体试餐后,应用双探头单光子发射计算机断层成像仪(SPECT)即刻对胃肠功能正常的受试者同时行前、后位动态显像。影像采集结束后,在胃区勾划感兴趣区。经计算机处理,获得其时间-放射性曲线,分别计算前、后位胃半排空时间及30min胃排空率。结果 40例胃肠功能正常者,前、后位胃半排空时间及30min胃排空率分别为(12.13±2.90)min,(11.17±3.00)min,(78.72±8.60)%,(79.34±8.96)%.前、后位胃半排空时间比较,两者差异有统计学意义(P<0.05);前、后位30min胃排空率比较,差异无统计学意义(P>0.05)。前、后位胃半排空时间及30min胃排空率的95%置信区间分别为(12.13±5.69)min,(11.17±5.87)min,(78.72±16.85)%,(79.34±17.57)%.结论液体试餐前、后位胃半排空时间有差异,前位采集时受影响因素较少,建议取前位采集图像;前、后位30min胃排空率比较,差异没有统计学意义,可取前位或后位采集图像。上述指标的95%置信区间为临床提供了前、后位胃半排空时间及30min胃排空率的正常参考值及异常判断标准。
OBJECTIVE: To compare the anterior and posterior dynamic imaging of gastric radionuclide imaging using ~ (99m) technetium-diethyl-triamine pentaacetic acid (~ (99m) Tc-DTPA) A simple and accurate method of gastric emptying function test, and to provide normal and abnormal gastric emptying function of quantitative reference. Methods After oral administration of ~ (99m) Tc-DTPA liquid, the double-probe single-photon emission computerized tomography (SPECT) was used to simultaneously conduct the anterior and posterior dynamic imaging of the subjects with normal gastrointestinal function. After the image acquisition, outline the area of interest in the stomach area. After the computer processing, the time-radiation curve was obtained, and the anterior and posterior gastric emptying time and gastric emptying rate at 30min were calculated respectively. Results The gastric emptying time and gastric emptying rate at the anterior and posterior stages were (12.13 ± 2.90) min, (11.17 ± 3.00) min, (78.72 ± 8.60)% and (79.34 ± 8.96)% respectively. There was significant difference between the two groups (P <0.05). There was no significant difference in gastric emptying rate between anterior and posterior position 30min (P> 0.05). The 95% confidence intervals of anterior and posterior gastric emptying time and 30 min gastric emptying rate were (12.13 ± 5.69) min, (11.17 ± 5.87) min and (78.72 ± 16.85)% and (79.34 ± 17.57)%, respectively. Conclusion There is a difference in half-time of gastric emptying before and after gastroscopy in the liquid sample, less affected factors in the anterior-posterior sampling. It is recommended to take the anterior digit to collect the images. There is no significant difference in the gastric emptying rate between the anterior and posterior positions for 30min, It is advisable to capture the image before or after. The 95% confidence interval of the above indexes provided the clinical reference values of the anteroposterior and posterior gastric emptying times and the gastric emptying rate of 30 minutes and the abnormality judgment standard.