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目的:探讨检测毛细支气管炎患儿肌酸激酶同工酶(CK-MB)和心肌肌钙蛋白Ⅰ(CTnI)的临床价值。方法:选择毛细支气管炎住院患儿85例为观察组,另选择同期非感染性疾病住院患儿75例为对照组。观察组与对照组分别于入院次日晨起和入院当天采集静脉血2ml送检,采用全自动生化分析仪,以赖氏比色法检测心肌酶谱及CTnI水平。结果:观察组心肌酶谱和CTnI水平均显著高于对照组(P<0.05);CK-MB异常率41.2%,CTnI异常率8.2%,分别显著高于对照组的13.3%和1.3%(P<0.05)。结论:CK-MB和CTnI对诊断毛细支气管炎患儿早期心肌损害具有重要参考价值。
Objective: To investigate the clinical value of detecting CK-MB and CTnI in children with bronchiolitis. Methods: 85 children with bronchiolitis were selected as the observation group, and 75 children hospitalized with non-infectious diseases in the same period were selected as the control group. The observation group and the control group were collected on the morning of admission and on the day of admission, 2ml venous blood samples were collected, using automatic biochemical analyzer, myocardial colorimetric detection and CTnI level by Lai’s colorimetry. Results: The levels of myocardial enzymes and CTnI in the observation group were significantly higher than those in the control group (P <0.05). The abnormal rates of CK-MB and CTnI were 41.2% and 8.2%, respectively, which were significantly higher than those in the control group (13.3% and 1.3%, P <0.05). Conclusion: CK-MB and CTnI have important reference value for the diagnosis of early myocardial damage in children with bronchiolitis.