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非甾体类抗炎药(NSAID)具有良好的解热、镇痛、消炎及抗风湿作用,但不良反应多见,本文通过复习近年文献,对NSAID的不良反应加以综述,并着重讨论其皮肤反应。美国1981年最常用的100种药物中,NSAID就有7种(阿司匹林第7位,布洛芬第12位)。美国皮肤病学会药物副作用反应报告系统(ADRRS)近年统计,NSAID可以引起135种不良反应,且在同一化学分类中的药物可发生类似的不良反应。NSAID引起的皮疹种类较多,约2～20％的患者可发生此反应(附表)。一、阿司匹林阿司匹林自1853年问世以来,至今在临床仍占有重要地位。我们通过临床和实验室研究,发现将其
Non-steroidal anti-inflammatory drugs (NSAIDs) have good antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects, but adverse reactions are more common. In this paper, reviews of recent literature, the adverse reactions of NSAID were reviewed, reaction. Among the 100 most commonly used drugs in the United States in 1981, there were 7 NSAIDs (aspirin 7, ibuprofen 12). In recent years, the American Dermatological Drug Reaction Report System (ADRRS) has reported that NSAIDs can cause 135 adverse reactions, and similar adverse reactions may occur in the same chemical classification. NSAID caused by more types of rash, about 2 to 20% of patients with this reaction (Schedule). First, aspirin Since its inception in 1853, aspirin still occupies an important position in the clinic. We found it through clinical and laboratory research