Semidominant heridity of absence-like seizures in tremor rat.

• 作 者: CaiJi-qun KumatoshiIshihara Ry
• 机 构: Dept.ofPharmacology,DeptofPharmacother,Neurosurg.,Inst.Lab.Anim.,NagisaHosp.
• 出 处: 中国药理通讯
• 发表日期: 2004年2期
• 关键词: 半显性遗传 震颤 大鼠 大脑皮层 脑电图 电生理学

The tremor rat (tm/tm) exhibits absence-like seizures characterized by 5 -7 Hz spike-wave complexes in cortical and hippocampal EEG. Recently, the TM rat has been found to be devoid of the asp) artoacylase (asp gene responsible for metabolizing N-acetyl a