青年人与老年人肺癌手术治疗结果的对比分析

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采用STATA5.0统计软件对111例≤40岁的青年人及53例≥70岁老年人肺癌的外科治疗病历建立数据库并进行统计分析。总结治疗结果,探讨其临床及影响预后因素的差异。2组间一般临床结果差异的显著性检验用卡方检验,生存率用寿命表法计算,生存率差异显著性检验用Logrank检验。结果显示:青年组与老年组胸痛、气短症状发生率分别为46.0%与18.9%、46.0%与28.3%;小细胞癌的比例分别为18.9%与5.7%;全肺切除率分别为21.6%与3.8%。青年组与老年组鳞癌、Ⅰ期病变的5a生存率分别为53.5%与20.9%、61.6%与52.0%。结果表明:青年组胸痛、气短症状发生率,小细胞癌的比例及全肺切除率均显著地高于老年组。青年组鳞癌及Ⅰ期病变的5a生存率均显著地高于老年组 STATA 5.0 statistical software was used to establish a database of 111 patients with ≤ 40 years of age and 53 patients with ≥ 70 years of age for surgical treatment of lung cancer. Summarize treatment outcomes and explore their clinical and prognostic factors. The significant test for the difference between the general clinical outcomes of the two groups was performed using the chi-square test. The survival rate was calculated using the life table method, and the significant difference in survival rates was tested using Logrank. The results showed that the rates of chest pain and shortness of breath symptoms were 46.0% and 18.9%, 46.0% and 28.3% in the young and elderly groups, respectively; the proportion of small cell carcinoma was 18.9% and 5.9%, respectively. 7%; Pneumonectomy rates were 21.6% and 3.8%, respectively. The 5-year survival rates of squamous cell carcinoma and stage I lesions in the young and elderly groups were 53.5% and 20.9%, 61.6%, and 52.0%, respectively. The results showed that the incidence of chest pain, shortness of breath symptoms, and the proportion of small cell carcinoma and pneumonectomy in the young group were significantly higher than those in the old group. The 5-year survival rate of squamous cell carcinoma and stage I lesions in the young group was significantly higher than that of the elderly group.
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