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中药排石汤治疗胆石病,具有排石和控制胆道急性炎症的效果,已为大量的临床观察所证实。实验研究证明排石汤有增加胆汁分泌量、舒张Oddi氏括约肌、收缩胆囊和抑制细菌的作用。 我们在临床工作中还注意到,患者在服用排石汤期间,其T管胆汁中的沉淀较暂停服药期间为少,并进一步通过胆汁沉淀压积的实验肯定了这一现象。为寻求其作用原理,我们观察了排石汤对T管胆汁中β-葡萄糖醛酸甙
The traditional Chinese medicine Paishi Decoction for the treatment of cholelithiasis has the effect of rowing stones and controlling the acute inflammation of the biliary tract and has been confirmed by a large number of clinical observations. Experimental studies have shown that Paishitang has the effect of increasing the secretion of bile, relaxing the sphincter of Oddi, contracting the gallbladder, and inhibiting bacteria. We also noticed in clinical work that during the course of taking Paishitang, the patient’s T-tube bile was precipitated less frequently than during the suspension of drug use, and this was further confirmed by experiments of cholestatic sedimentation. In order to search for its principle of action, we observed that Paishi Decoction is a beta-glucuronidase in the bile of T-tube.