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目的探讨沐舒坦与固尔苏用于新生儿呼吸窘迫综合征的临床治疗效果。方法将100例患有新生儿呼吸窘迫综合征的早产低体重儿随机分为治疗组和对照组各50例,在两组给予同样的综合治疗的基础上分别给予沐舒坦与固尔苏治疗,观察两组患儿血气指标、X线、临床症状等变化,对其临床治疗效果进行评估。结果两组患儿临床治疗效果对比差异无统计学意义(P>0.05),但治疗组患儿体温降至正常时间、肺部体征消失时间以及疗程均短于对照组,差异有统计学意义(P<0.05)。结论在临床上,治疗新生儿呼吸窘迫综合征应用沐舒坦与固尔苏的疗效没有明显差异,均能够获得较好的治疗效果。但沐舒坦要比固尔苏起效稍快,总体治疗效果优于固尔苏,因此临床上应尽早、足量使用沐舒坦,避免因出现肺动脉高压而致持续性动脉导管开放。
Objective To investigate the clinical effect of mucosolvan and celiac on neonatal respiratory distress syndrome. Methods 100 cases of neonatal low birth weight preterm infants with respiratory distress syndrome were randomly divided into treatment group and control group of 50 cases in both groups given the same comprehensive treatment on the basis of the respectively given Shu Shu Tan and Guer Su treatment, The changes of blood gas indexes, X-ray and clinical symptoms in both groups were observed, and the clinical effect was evaluated. Results There was no significant difference in the clinical effect between the two groups (P> 0.05). However, the body temperature in the treatment group dropped to normal time, the disappearance time of lung signs and the duration of treatment were shorter than those in the control group (P> 0.05) P <0.05). Conclusion Clinically, the treatment of neonatal respiratory distress syndrome Mu Shu Teng and Guer Su effect no significant difference, can get better treatment. However, Mu Shu Shoutun slightly faster than the onset of Guer Su, the overall effect of treatment is superior to Guer Su, so clinically as early as possible, the full use of ambroxol to avoid the occurrence of pulmonary hypertension due to persistent ductus arteriosus open.