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人参具有多种药理作用,临床应用极为广泛。现代药理学研究证明,人参茎叶部与根部具有相似的药理活性,国内外许多文献报道人参茎叶总皂甙(GNS)对机体各系统及多种酶活性均有明显的调节作用。我们以小鼠早期精细胞微核试验和初级精母细胞染色体畸变试验为指标,检测GNS对小鼠雄性生殖细胞有无损害作用。
Ginseng has a variety of pharmacological effects, and its clinical application is extremely extensive. Modern pharmacology studies have shown that the ginseng stems and leaves have similar pharmacological activities to the roots. Many literatures at home and abroad have reported that Ginseng stem and leaf total saponins (GNS) have significant effects on the body’s various systems and various enzyme activities. We used the mouse sperm cell micronucleus test and primary spermatocyte chromosome aberration test as indicators to determine whether GNS had any damage to male mouse germ cells.