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目的了解呼吸道合胞病毒(RSV)在小儿急性下呼吸道感染中的发生率和临床特征。方法对我院2007年10月—2008年10月临床诊断为急性下呼吸道感染的住院患儿556例行痰直接免疫荧光法检测呼吸道合胞病毒抗原。结果556例患儿中,阳性193例,阳性率34.71%,其中男132例(23.74%),女61例(10.97%),男女发病比例为2.16:1。全年均可检出RSV,发病率最高的是11、12、1、2月份(43.06%),最低的是5~8月份(16.36%)。RSV感染多见于3岁以下,尤以6个月以下患儿感染率最高(44.50%)。结论呼吸道合胞病毒是引起小儿急性下呼吸道感染的主要病原,特别是婴幼儿感染率最高。
Objective To understand the incidence and clinical characteristics of respiratory syncytial virus (RSV) in children with acute lower respiratory tract infection. Methods 556 inpatients with acute lower respiratory tract infection who were clinically diagnosed in our hospital from October 2007 to October 2008 were tested for sputum syncytial virus antigen by direct immunofluorescence. Results Of the 556 children, 193 were positive, with a positive rate of 34.71%. There were 132 males (23.74%) males and 61 females (10.97%) males. The incidence of males and females was 2.16: 1. RSV could be detected throughout the year, the highest incidence rates were in November, December, January and February (43.06%) and lowest in May-August (16.36%). RSV infection more common in children under 3 years of age, especially in children under 6 months the highest infection rate (44.50%). Conclusion Respiratory syncytial virus is the main cause of acute lower respiratory tract infection in children, especially in infants and young children with the highest infection rate.