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目的探讨纤溶酶联合丁苯酞软胶囊治疗急性脑梗死的神经功能缺损的效果。方法 70例急性脑梗死患者随机分为治疗组和对照组组,每组35例。对照组应用静脉滴注纤溶酶100 U,1次/d。14 d为1个疗程。治疗组在对照组治疗基础上加用丁苯酞软胶囊进行治疗,200 mg,口服,4次/d,14 d为1个疗程。采用NIHSS评分、治愈率、有效率评价两组治疗效果。结果治疗组治疗后神经功能缺失评分较治疗前明显改善,并且疗效显著优于对照组(P<0.05),与对照组相比,治疗组治愈率及总有效率均明显提高(P<0.05)。结论纤溶酶联合丁苯酞软胶囊治疗急性脑梗死疗效确切,安全可靠。
Objective To investigate the effect of fibrinolytic combined with butylphthalide soft capsule in the treatment of neurological deficits in acute cerebral infarction. Methods Seventy patients with acute cerebral infarction were randomly divided into treatment group and control group, 35 cases in each group. Control group intravenous infusion of plasmin 100 U, 1 time / d. 14 d for a course of treatment. The treatment group in the control group plus butylphthalide soft capsule treatment, 200 mg, orally, 4 times / d, 14 d for a course of treatment. The NIHSS score, cure rate and effective rate were used to evaluate the therapeutic effects in both groups. Results After treatment, the score of neurological deficit in the treatment group was significantly improved compared with that before treatment, and the curative effect was significantly better than that of the control group (P <0.05). Compared with the control group, the cure rate and total effective rate of the treatment group were significantly increased (P <0.05) . Conclusion The effect of plasmin combined with butylphthalide soft capsule in the treatment of acute cerebral infarction is effective, safe and reliable.