论文部分内容阅读
目的 :观察醋酸奥曲肽治疗食管静脉曲张破裂出血的疗效。方法 :90例食管静脉曲张破裂出血患者分为两组 ,治疗组 6 0例用醋酸奥曲肽治疗 ,对照组 30例用奥曲肽治疗 ,观察并比较两组的疗效、止血时间、输血量。结果 :治疗组总有效率为 95 % ,对照组总有效率为 90 .0 %。两组间无统计学差异 (P >0 .0 5 )。两组止血成功患者在 2 4 ,4 8h的输血量分别为 :治疗组 (314 .3± 12 9.5 )ml,(44 5 .2± 312 .9)ml;对照组 (46 0 .0± 2 5 0 .3)ml,(6 6 1.5± 386 .3)ml,两组比较在统计学上有明显差异 (P<0 .0 5 )。结论 :醋酸奥曲肽的临床疗效优于奥曲肽 ,醋酸奥曲肽能有效、安全地治疗食管静脉曲张破裂出血。
Objective: To observe the efficacy of octreotide acetate in the treatment of esophageal variceal bleeding. Methods: Ninety patients with esophageal variceal bleeding were divided into two groups. The treatment group was treated with octreotide acetate and the control group with octreotide. The curative effect, bleeding time and blood transfusion were observed and compared between the two groups. Results: The total effective rate was 95% in the treatment group and 90.0% in the control group. There was no significant difference between the two groups (P> 0.05). The amount of blood transfusions in two groups of successful hemostasis patients at 24 and 48 hours were: (314.3 ± 12 9.5) ml, (44.5 ± 312.9) ml in the treatment group, (46.0 ± 0.2) 5 0 .3) ml, (6 6 1.5 ± 386 .3) ml respectively. There was a statistically significant difference between the two groups (P <0.05). Conclusion: The clinical efficacy of octreotide acetate is superior to that of octreotide. Octreotide acetate can effectively and safely treat esophageal variceal bleeding.