乳酸左氧氟沙星与头孢呋辛3日疗法随机对照治疗尿路感染76例临床评价

• 作 者: 张玉强 梅长林 吴俊 张黎明 赵学智
• 机 构: 上海长征医院!上海200003,上海长征医院!上海200003,上海长征医院!上海200003,上海长征医院!上海200003,上海长征医院!上海200003
• 出 处: 中国抗生素杂志
• 发表日期: 1999年S1期
• 关键词: 乳酸左氧氟沙星 尿路感染 头孢呋辛 3日疗法 不良反应率 左氧氟沙星片 细菌清除率 多重耐药菌 药物滥用 血药浓度

　以乳酸左氧氟沙星片为试验药与头孢呋辛随机对照,用3 日疗法治疗急性尿路感染76 例。乳酸左氧氟沙星200m g,每日2 次口服;头孢呋辛250m g,每日2 次口服,疗程均为3d。结果试验药组与对照药组总有效率分别为94.7% 和89.5% 。细菌清除率分别为93.3% 和88.5% ,药物不良反应率分别为7.9% 和13% 。结果证明乳酸左氧氟沙星3 日疗法治疗急性尿路感染是安全、有效的药物之一。

Levofloxacin lactate tablets as the test drug and cefuroxime were used as a randomized control, with 3-day treatment of 76 cases of acute urinary tract infection. Levofloxacin lactate 200m g, 2 times a day orally; cefuroxime 250m g, 2 times a day orally, treatment are 3d. Results The total effective rate of the test drug group and the control drug group was 94.7% and 89.5% respectively. Bacterial clearance rates were 93.3% and 88.5%, respectively, with adverse drug reaction rates of 7.9% and 13%, respectively. The results show that levofloxacin lactate 3-day treatment of acute urinary tract infection is safe and effective drug.