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目的探讨感染性心内膜炎(IE)内外科综合治疗的方法和疗效。方法1988年1月至2007年4月,我院281例IE患者在接受内科抗感染治疗的同时,采取积极的外科手术治疗。结果本组术后早期死亡9例(3.2%),其中6例因感染性心内膜炎不能控制,3例因严重低心排综合症引发多器官衰竭。术后主要并发征包括:低心排综合征23例,急性肾功能不全36例,上消化道出血15例,Ⅲ度房室传导阻滞6例,经精心治疗,本组272例患者痊愈出院。结论感染性心内膜炎单纯内科治疗死亡率很高,而尽早确诊,适时手术和内外科综合治疗则具有很好的疗效。
Objective To explore the method and efficacy of internal and external surgical treatment of infective endocarditis (IE). Methods From January 1988 to April 2007, 281 patients with IE in our hospital underwent active surgical treatment while receiving medical anti-infective therapy. Results Nine patients (3.2%) died of early postoperative complications. Six of them were unable to control due to infective endocarditis and three caused multiple organ failure due to severe low cardiac output syndrome. The main postoperative complications include: low cardiac output syndrome in 23 cases, acute renal insufficiency in 36 cases, 15 cases of upper gastrointestinal bleeding, Ⅲ degree atrioventricular block in 6 cases, after careful treatment, the group of 272 patients were discharged . Conclusions Infective endocarditis alone medical treatment of high mortality rate, and as soon as possible diagnosed, timely surgery and internal medicine combined treatment has a good effect.