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目的：探讨原发性甲状旁腺机能亢进症的诊断要点，提高本病的正确诊断率。方法：对１９８６～１９９６年手术治疗并经病理证实的２２例原发性甲状旁腺机能亢进症的诊断进行回顾性分析。结果：原发性甲状旁腺机能亢进症临床误诊率较高。临床表现复杂多样，缺乏特异性；医生对本病缺乏认识和诊治经验；实验室检查的局限性以及医生对实验室检查结果的机械性解释是误诊的重要原因。结论：提高对本病的认识，掌握其临床表现，重视早期症状，对疑似病例反复多次测定血钙和血磷、２４小时尿钙和尿磷，以及血清碱性磷酸酶等，并结合临床及Ｘ线检查综合分析是正确诊断的主要根据。
Objective: To investigate the diagnosis of primary hyperparathyroidism and improve the correct diagnosis of the disease. Methods: A retrospective analysis of 22 cases of primary hyperparathyroidism diagnosed surgically from 1986 to 1996 was performed. Results: The primary misdiagnosis rate of hyperparathyroidism is high. Complex and diverse clinical manifestations, the lack of specificity; doctors lack of understanding of the disease and diagnosis and treatment experience; laboratory limitations and the doctor’s laboratory interpretation of the results of mechanical interpretation is an important reason for misdiagnosis. Conclusion: To improve the understanding of the disease, to grasp its clinical manifestations, pay attention to early symptoms, the repeated repeated determination of serum and serum phosphorus, 24-hour urinary calcium and urinary phosphorus, and serum alkaline phosphatase in suspected cases, combined with clinical And X-ray examination Comprehensive analysis is the main basis for the correct diagnosis.